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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a protein involved in allergic reactions and responses to parasites.

Quick summary

["IgE helps identify allergies or immune responses that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61210-1
Short code
Onion IgE/IgE total %
Synonyms
Onion IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgE Measure?

IgE (Immunoglobulin E) is a type of antibody produced by your immune system in response to allergens (substances like pollen, dust, or certain foods) or parasitic infections. Elevated IgE levels may suggest allergies, asthma, or other immune-related conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that could indicate allergies. It can also help diagnose conditions like allergic asthma or certain parasitic infections.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re nervous, let your healthcare provider know so they can help you relax.

What Does a High or Low IgE Level Mean?

High IgE levels often point to allergies or hypersensitive immune reactions. Very high levels might suggest conditions like severe allergies, asthma, or parasitic infections. Low IgE levels are less common and may indicate immune deficiencies or other underlying health issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are often linked to allergies (e.g., to pollen, pet dander, or foods), asthma, or parasitic infections. Sometimes, it can also be due to chronic inflammatory conditions or certain immune disorders.
What if my IgE test is normal but I still have allergy symptoms?
A normal IgE level doesn’t rule out allergies entirely. Other tests, like skin prick tests or allergy-specific IgE tests, may be needed to identify specific triggers. Your doctor may recommend further evaluation based on your symptoms.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, infections, or treatments. If your levels are elevated, your doctor may monitor them over time to assess how your body responds to allergies or treatments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy