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Opioid Substance Concentration (Urine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of opioids, such as codeine, morphine, or hydrocodone, in your urine. It helps detect recent opioid use, often ordered for pain management, addiction screening, or pre-employment or legal evaluations.

Quick summary

["Detects recent opioid use through urine testing for common painkillers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95796-9
Short code
Opioids Pnl Ur Scn
Synonyms
Opioids Pnl Ur Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if you’re being evaluated for pain management, suspected substance use, pre-employment screening, legal reasons, or to monitor opioid therapy. It helps assess whether opioids are in your system and at what levels.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample in a private area. If you’re under 18 or pregnant, check with your provider first—some tests may require different instructions.

What Happens During the Test?

A trained staff member will collect your urine sample in a sterile container. The lab will then analyze it using a sensitive immunoassay method to detect opioids.

What Are Common Opioids Detected?

This test screens for several opioids, including prescription painkillers like oxycodone, hydrocodone, morphine, and fentanyl, as well as illicit opioids like heroin. Results are reported as positive or negative, not specific to the type.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate recent opioid use, which can guide treatment decisions, such as adjusting pain management plans, assessing addiction risks, or confirming compliance with prescribed medications. Negative results suggest no detectable opioids in your system. Always discuss results with your healthcare provider for personalized interpretation.

Short name

Urine Opioid Screen

Frequently asked questions

What does a positive result mean?
A positive result means opioids were found in your urine, indicating recent use. This could be due to prescribed medication, illegal use, or both. Your provider will discuss next steps, such as further testing or changes to your treatment plan.
Can I drink water before the test?
Yes, you can drink water as usual unless your provider specifies otherwise. Avoid excessive fluids or certain foods/drinks that might interfere with the test results.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your provider to review the results and any next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy