Serum or plasma total protein concentration (qualitative screening)
This test measures the overall amount of protein in your blood serum or plasma, which includes both albumin and globulin proteins. It helps assess overall protein status and potential issues like malnutrition, kidney disease, or liver problems.
["A qualitative screening helps identify abnormal protein levels that may require further testing."]
Key facts at a glance
- LOINC
- 18495-2
- Short code
- O+P sp3 Stl Tri Stn
- Synonyms
- O+P sp3 Stl Tri Stn
- Category
- chemistry
- Sample
- stool
- Container
- Clean container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- trichrome-stain
- Specimen volume
- 5 g
- Stability
- Refrigerated: 24h, Frozen: 7d
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, or severe malnutrition. It can also be part of routine health evaluations or when symptoms like swelling, fatigue, or unexplained weight loss appear.
What to Expect Before the Test
No special preparation is needed. You may have a blood draw, where a small amount of blood is taken from a vein in your arm. If a urine sample is used, you might be asked to collect a midstream sample at home. Always follow your provider’s instructions for any fasting or fluid restrictions.
What Happens During the Test?
Blood or urine is sent to a lab for analysis. The test is qualitative, meaning it provides a yes/no or high/low result rather than a precise number. Results are typically reviewed within hours or days, depending on lab processes.
What Are Possible Results?
Results may be categorized as normal, low, or high. Low protein levels could suggest conditions like malnutrition, kidney disease, or liver failure. High levels might indicate dehydration, multiple myeloma, or severe inflammation. Your provider will discuss these findings with you.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein levels can signal serious health concerns. Low protein levels may indicate poor nutrient absorption, chronic diseases, or excessive protein loss (e.g., from kidney disease). High protein levels could reflect dehydration, certain cancers, or immune system disorders. Early detection helps guide treatment plans.
Short name
Total Protein (Qualitative Screen)
Frequently asked questions
What Does a Low Total Protein Level Mean?
What Does a High Total Protein Level Mean?
Can Diet Affect This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy