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Organic Acid Profile (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of various organic acids in your urine over a 24-hour period. Organic acids are compounds produced by your body that can help identify metabolic or genetic conditions.

Quick summary

["This test helps diagnose conditions affecting how your body breaks down certain substances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53136-8
Short code
Organic Acids Pattern Fld-Imp
Synonyms
Organic Acids Pattern Fld-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if you have symptoms like unusual smells in urine, unexplained fatigue, or signs of metabolic disorders. It’s also used to monitor conditions like mitochondrial disorders, organic acidemias, or inborn errors of metabolism.

What Does the Test Involve?

You’ll collect all your urine over 24 hours in a special container. The collected urine is then sent to a lab for analysis using advanced techniques like high-performance liquid chromatography (HPLC).

What to Expect Before the Test

No special preparation is needed, but you should drink enough fluids to produce urine throughout the day. Avoid certain medications or supplements that might interfere with results, as directed by your provider.

What to Expect During the Test

You’ll collect urine in a container provided, changing the bag every few hours. The test involves emptying your bladder into the container at regular intervals. The sample is sealed and sent to the lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Organic Acid Urine Test

Frequently asked questions

How long does it take to get results?
Results are typically ready within 1 to 2 weeks after the lab processes your urine sample. Your healthcare provider will discuss the findings with you during a follow-up visit.
What does it mean if my results are abnormal?
Abnormal results may suggest an underlying metabolic condition that needs further testing or medical management. Your doctor will work with you to determine the next steps, which could include additional tests, dietary changes, or treatment options.
Can I take supplements or medications before the test?
Some supplements or medications may interfere with test results. Always inform your healthcare provider about all medications, vitamins, or supplements you’re taking before starting the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy