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Organic acids profile (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures multiple organic acids in your blood, which can help identify metabolic or genetic conditions affecting how your body processes certain nutrients.

Quick summary

["Helps diagnose rare metabolic disorders by detecting abnormal acid buildup in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17387-2
Short code
Organic Acids SerPl-aCnc
Synonyms
Organic Acids SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Organic Acids Are Measured?

Your blood sample will be analyzed for a variety of organic acids, including but not limited to methylmalonic acid, propionic acid, and lactic acid. These acids are byproducts of normal metabolic processes, but elevated levels may indicate underlying health issues.

Why This Test Might Be Ordered?

Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, developmental delays in children, or unexplained health problems that suggest metabolic disorders.

Sample Collection and Preparation

A blood sample will be drawn from a vein in your arm. The sample is typically sent to a lab for high-performance liquid chromatography (HPLC) analysis to measure organic acid levels accurately.

Common Conditions Monitored

Elevated or abnormal levels of certain organic acids can be linked to conditions such as mitochondrial disorders, organic acidemias, or other metabolic syndromes. This test is often used in newborn screening or for ongoing monitoring in patients with suspected metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Organic Acid Test (Serum/Plasma)

Frequently asked questions

What does a 'normal' result mean for me?
A 'normal' result means your organic acid levels are within expected ranges for your age and health status. However, this does not rule out all metabolic conditions—further testing may still be needed if symptoms persist.
How long will it take to get my results?
Results are typically available within 2–5 business days, depending on lab processing times. Your healthcare provider will discuss findings with you during a follow-up visit.
Can I eat or drink before this test?
For most organic acid tests, you may fast for 8–12 hours before the blood draw, but always follow your provider’s specific instructions to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy