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Organic acids profile (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of various organic acids in your blood, which can help identify metabolic or genetic conditions.

Quick summary

["Organic acids may signal underlying health issues that require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10837-3
Short code
Organic Acids SerPl Ql
Synonyms
Organic Acids SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fatigue, muscle weakness, or unusual smells in your breath or urine. It can also be used to diagnose or monitor conditions such as mitochondrial disorders, metabolic disorders, or inherited metabolic diseases.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Wear a loose shirt for easy access to your arm.

How the Test Works

A small amount of blood is drawn from a vein in your arm. The blood sample is then analyzed to detect specific organic acids, often using advanced laboratory techniques like chromatography or mass spectrometry.

Possible Results and Interpretation

Results are compared to reference ranges for healthy individuals. Elevated or abnormal levels of certain organic acids may indicate metabolic imbalances or genetic disorders that require specialized care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Organic Acids Blood Test

Frequently asked questions

What might cause abnormal results?
Abnormal organic acid levels can be caused by genetic mutations, mitochondrial disorders, or certain metabolic syndromes. High levels may also appear in people with kidney issues or certain infections.
Can this test detect all metabolic disorders?
No, this test is a screening tool. Some conditions may require additional tests, such as genetic testing or further metabolic studies, for a full diagnosis.
How often should I get this test?
Your provider will determine the frequency based on your symptoms, medical history, and ongoing health needs. Follow-up may be scheduled if initial results are concerning.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy