Urinary Organic Acids Profile (Quantitative)

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like unusual fatigue, muscle weakness, or unexplained health issues that could be linked to metabolic disorders. It’s also used in diagnosing conditions such as mitochondrial disorders, inborn errors of metabolism, or other metabolic syndromes.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before collecting your urine sample. Follow your provider’s instructions carefully to ensure accurate results.

How the Test Works

A urine sample is collected, often over a 24-hour period or as a single sample, and analyzed using advanced laboratory techniques (such as high-performance liquid chromatography) to measure the concentration of organic acids.

Common Conditions Monitored

This test helps detect abnormalities in organic acid metabolism, which can be linked to conditions like maple syrup urine disease, methylmalonic acidemia, or other metabolic disorders. It may also be used in newborn screening or ongoing monitoring for patients with known metabolic conditions.