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Bilirubin, Total (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin helps diagnose liver and bile duct issues, including jaundice and gallbladder problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10389-5
Short code
Other Bld Prod BPU
Synonyms
Other Bld Prod BPU
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like jaundice (yellowing of skin or eyes), dark urine, pale stools, or unexplained fatigue. It’s also used to monitor liver function, detect bile duct blockages, or check for conditions like hemolytic anemia or liver disease.

What to Expect Before the Test

You won’t need special preparation. For blood tests, a small needle will draw blood from a vein in your arm. If you’re nervous, let your healthcare provider know so they can help you relax.

What the Results Mean

Higher-than-normal bilirubin levels may indicate problems with red blood cell breakdown, liver function, or bile flow. Lower levels are usually normal but can sometimes signal liver issues in rare cases. Always discuss your results with your doctor.

Common Conditions Linked to Bilirubin Levels

Elevated bilirubin is often seen in conditions like jaundice (from liver or bile duct issues), hemolytic anemia (rapid red blood cell destruction), or liver diseases (like hepatitis or cirrhosis). Low levels are less common but may sometimes appear in liver disorders or certain genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bilirubin

Frequently asked questions

How long does it take to get my bilirubin test results back?
Results are typically available within 1 to 3 business days, depending on your lab. Follow-up with your doctor to review them and discuss next steps.
Can I eat or drink anything before this test?
No special diet or fasting is required for this test. However, if your doctor has other instructions (like fasting for other tests), follow those instead.
Is there anything I should do to prepare for this blood test?
Rest assured that blood tests are generally safe. If you have a clotting disorder or are on blood thinners, let your lab technician know beforehand to ensure proper care.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy