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Ovalbumin-Specific IgE Antibody Test by Radioallergosorbent Testing (RAST)

Published: August 9, 2026Updated: August 17, 2026

This test measures IgE antibodies directed against ovalbumin, a major egg protein. It may be used to help evaluate a suspected egg allergy.

Quick summary

["A positive result indicates an immune response to ovalbumin, but it must be interpreted with allergy symptoms and medical history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102482-7
Short code
Ovalb IgE RAST
Synonyms
Ovalb IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Ovalbumin?

Ovalbumin is a protein found in egg whites. Some people have an immune response to this protein and may have symptoms after eating eggs or exposed to egg products.

What Does the Test Measure?

The test detects ovalbumin-specific IgE antibodies. These antibodies are part of the immune response associated with allergic sensitization.

How Is the Test Performed?

A blood sample is analyzed using a radioallergosorbent method, commonly called RAST, or a comparable laboratory method for detecting allergen-specific IgE.

How Are Results Interpreted?

A positive result suggests sensitization to ovalbumin, while a negative result makes an immediate ovalbumin allergy less likely. Results should be interpreted by a healthcare professional because test findings do not always match symptoms.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Ovalbumin-specific IgE testing can help identify an allergic cause of symptoms such as hives, swelling, wheezing, vomiting, or other reactions associated with egg exposure. It does not by itself confirm that every exposure will cause symptoms, and a result should be considered alongside the clinical history and, when needed, an allergy evaluation.

Short name

Ovalbumin IgE (RAST)

Frequently asked questions

What Does a Positive Ovalbumin IgE Result Mean?
It means that ovalbumin-specific IgE was detected, indicating immune sensitization. It does not automatically establish a symptomatic egg allergy or show how severe a reaction would be.
Can I Eat Eggs With a Positive Result?
Do not assume that all eggs must be avoided based on this test alone. Ask an allergist or your clinician whether the result reflects your symptoms and whether supervised food testing is appropriate.
Does a Negative Result Rule Out Egg Allergy?
No. A negative result makes immediate ovalbumin allergy less likely, but some reactions are caused by other egg proteins, are not IgE-mediated, or may not be detected by this test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy