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Serum Lipoprotein(a) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a) in your blood, a type of cholesterol-like particle that includes both cholesterol and a protein called apolipoprotein(a). Lp(a) is linked to increased risk of heart disease and blood clots.

Quick summary

["Lipoprotein(a) levels may help assess your risk for cardiovascular issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53352-1
Short code
Oval fat bodies # Ur Comp Assist
Synonyms
Oval fat bodies # Ur Comp Assist
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
computer-assisted
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with apolipoprotein(a). While it shares some traits with other cholesterol particles, it behaves differently in the body. High levels of Lp(a) can contribute to plaque buildup in arteries and increase the risk of heart attacks or strokes, even in people without other risk factors like high blood pressure or diabetes.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of early heart disease, a history of blood clots, or if you have other risk factors for cardiovascular problems. It may also be used to monitor treatment for conditions affecting blood vessels or cholesterol levels.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab for analysis. The test measures the concentration of lipoprotein(a) in your serum (the liquid part of blood after clotting).

What Are Possible Results?

Results are typically reported as a numerical value representing the concentration of lipoprotein(a) in milligrams per deciliter (mg/dL) or another standardized unit. Your results will be compared to general reference ranges provided by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lipoprotein(a) (Lp(a))

Frequently asked questions

What Does High or Low Lp(a) Mean?
High levels of lipoprotein(a) are associated with an increased risk of cardiovascular diseases, such as coronary artery disease and peripheral artery disease. While not all high Lp(a) levels lead to immediate health risks, they may warrant further evaluation or lifestyle changes to reduce risk factors. Your doctor will discuss the implications of your specific result with you.
How Often Should I Get This Test?
The frequency of this test depends on your individual health needs, risk factors, and medical history. Your healthcare provider will determine if and when to repeat the test based on your overall health and any changes in your condition.
Can I Do Anything to Lower My Lp(a) Levels?
Currently, there are no medications specifically approved to lower lipoprotein(a) levels. However, managing other cardiovascular risk factors—such as maintaining a healthy diet, exercising regularly, not smoking, and controlling blood pressure and cholesterol—may indirectly support heart health. Some research suggests certain lifestyle changes or supplements might help, but more studies are needed. Always consult your healthcare provider before making changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy