Ovarian Malignancy Panel (Screening) – Serum/Plasma
This test measures certain substances in your blood that may help detect ovarian cancer or monitor its progression. It’s often used as part of a broader evaluation for suspected ovarian malignancy.
["Early detection of ovarian cancer may improve treatment outcomes."]
Key facts at a glance
- LOINC
- 104551-7
- Short code
- Ovarian malignancy (ROMA) panel SerPl
- Synonyms
- Ovarian malignancy (ROMA) panel SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test measures the level of a specific protein in your blood that is commonly associated with ovarian cancer. Doctors use this measurement, together with imaging and other findings, to help evaluate ovarian health, assess certain symptoms, and guide the next steps in your care.
The ovarian malignancy screening panel typically includes markers that reflect ovarian cancer activity, such as proteins or substances that may be elevated in cancerous tissue. These may include substances like CA-125 (a common ovarian cancer biomarker) and others identified through advanced testing methods.
You may need this test if you have symptoms that could point to an ovarian condition, such as persistent pelvic pain, bloating, or abdominal swelling, or if you have an ovarian mass that your doctor wants to evaluate more closely. It can also be used to monitor how treatment is working or to check for signs that the condition has returned during follow-up visits.
You may have this test if you have symptoms like persistent abdominal or pelvic pain, bloating, or unexplained weight changes. It’s also used in follow-up for women at higher risk due to family history, genetic conditions, or previous ovarian cancer diagnosis.
This test requires a blood sample, which is usually drawn from a vein in your arm. Fasting is generally not necessary, but always follow the specific instructions given by your doctor or the laboratory. Let your healthcare provider know about any medicines or supplements you take, and drink plenty of water beforehand to make the blood draw easier.
Blood is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. The test uses serum or plasma, depending on the specific methods applied.
The specimen used for this test is a small sample of your blood, collected into a special tube in the laboratory. Once received, the sample is analyzed with precise methods to measure the marker level, and the results are reported to your doctor, typically within a few business days.
The test may use immunoassays (like clia or fia) or other sensitive techniques to detect and quantify specific biomarkers. These methods help distinguish between normal and abnormal levels of substances linked to ovarian cancer.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Ovarian Cancer Biomarker Screen
Frequently asked questions
This screening panel helps identify women who may have ovarian cancer or are at higher risk. While no test is 100% accurate, elevated levels of certain biomarkers can signal the need for further investigation, such as imaging or biopsy.
A positive result may indicate a higher likelihood of ovarian cancer or other ovarian-related conditions. However, it doesn’t confirm the diagnosis alone. Your healthcare provider will discuss next steps, which may include additional tests or monitoring.
Yes, this screening panel can help detect ovarian cancer at earlier stages, which may improve treatment options and outcomes. However, it’s not foolproof and should be used alongside other clinical findings and imaging.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy