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Cortisol concentration in ovarian tissue (or adrenal gland) measured via immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures cortisol levels in a sample taken from ovarian tissue, often used to evaluate adrenal or ovarian function in conditions affecting steroid hormone production.

Quick summary

["Assessing hormone balance in conditions like adrenal insufficiency or ovarian disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11830-7
Short code
Ovary-R Diam.hilum-cort US.meas
Synonyms
Ovary-R Diam.hilum-cort US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or medical history suggesting issues with cortisol production, such as adrenal gland problems, ovarian dysfunction, or hormonal imbalances. It could also be part of a broader evaluation for conditions like Cushing’s syndrome, adrenal insufficiency, or congenital adrenal hyperplasia.

What to Expect Before the Test

The test involves a small tissue sample (likely from ovarian tissue) collected during a surgical procedure. Cortisol levels are measured in this sample using a specialized immunoassay method. You may need to follow specific instructions regarding fasting or medication adjustments before the procedure.

How the Results Are Interpreted

Results are compared to expected ranges for cortisol in ovarian tissue, though reference ranges can vary by lab and clinical context. Abnormal results may indicate either excessive or insufficient cortisol production, guiding further medical evaluation.

Potential Risks and Considerations

The procedure for tissue sampling carries general risks of infection, bleeding, or discomfort. Cortisol measurement itself is non-invasive but relies on accurate tissue sampling and lab precision. Discuss any concerns with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

What does cortisol in ovarian tissue tell us?
Cortisol is a critical steroid hormone produced by the adrenal glands but can also be produced in smaller amounts by the ovaries. Abnormal levels may signal underlying conditions affecting hormone synthesis, such as adrenal tumors, ovarian cysts, or genetic disorders. This test helps diagnose or monitor conditions that disrupt normal hormone production pathways.
How might my results affect my treatment?
If your results show abnormal cortisol levels, your healthcare provider may recommend additional tests (e.g., blood cortisol measurements, imaging, or genetic testing) to pinpoint the cause. Treatment could involve hormone replacement, medication adjustments, or management of underlying conditions like tumors or genetic syndromes.
Is this test the same as a standard blood cortisol test?
No. This test measures cortisol specifically in ovarian tissue, which differs from standard blood cortisol tests (e.g., morning serum cortisol). Tissue cortisol levels can reflect localized production or storage in the ovaries, offering unique insights for certain conditions not captured by blood tests alone.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy