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Uric Acid, Serum or Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of uric acid, a waste product from your body’s natural breakdown of certain foods and substances, found in your blood.

Quick summary

["Uric acid levels help assess kidney function and risk of certain conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57374-1
Short code
Oxalate 2h Ur-mCnc
Synonyms
Oxalate 2h Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like joint pain, kidney problems, or if they suspect conditions like gout, kidney stones, or certain types of arthritis. It may also be part of routine check-ups for people at higher risk of these issues, such as those with a family history of gout or kidney disease.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Bring any medications you’re taking, as some can affect results.

How the Test Works

A blood sample is drawn from a vein in your arm. The sample is then sent to a lab where it is analyzed to measure the uric acid level using a specialized technique, often high-performance liquid chromatography (HPLC) or a similar method.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). High levels may indicate conditions like gout, kidney disease, or certain cancers. Low levels might suggest dehydration or other metabolic issues, though this is less common.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High uric acid levels can contribute to gout, kidney stones, and cardiovascular risks. Low levels are less frequently significant but may warrant further evaluation if symptoms like fatigue or muscle weakness are present. Always discuss results with your healthcare provider for personalized interpretation.

Short name

Uric Acid

Frequently asked questions

What causes uric acid levels to be too high?
High uric acid can result from diet (rich in purines like red meat or seafood), kidney problems, certain medications, or metabolic conditions. Genetics may also play a role in some cases.
How can I lower my uric acid levels if my test is elevated?
Lifestyle changes such as reducing high-purine foods, staying hydrated, maintaining a healthy weight, and avoiding alcohol can help. Your doctor may also recommend medications or supplements if needed.
Does fasting affect uric acid test results?
Yes, fasting for 8–12 hours before the test may slightly lower uric acid levels, so it’s important to follow instructions to avoid misleading results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy