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Oxalate in Urine (Quantitative, 24-Hour Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of oxalate, a compound formed from vitamin C and other substances in your urine over a full day. Oxalate can contribute to kidney stones or other health issues if levels are consistently high.

Quick summary

["Assess urinary oxalate excretion to identify potential risks for kidney stones or metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12796-9
Short code
Oxalate sp8 p chal Ur-mCnc
Synonyms
Oxalate sp8 p chal Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have a history of kidney stones, certain digestive disorders (like inflammatory bowel disease), or symptoms such as pain in your back or side that could indicate kidney stones. It may also be used to monitor conditions affecting oxalate metabolism.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after midnight on one day and ending just after midnight the next. Follow your provider’s instructions carefully to ensure accurate results. Drink plenty of fluids during this time to help flush oxalates naturally.

What to Expect During the Test

No special preparation is needed beyond the 24-hour urine collection. Your sample will be sent to a lab for analysis using a high-performance liquid chromatography (HPLC) method to measure oxalate levels precisely.

What the Results Mean

Results help determine if your body is excreting oxalate at a level that could pose risks. High levels may suggest conditions like primary hyperoxaluria or malabsorption issues, while normal levels help rule out these concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urinary oxalate levels may increase the risk of forming calcium oxalate kidney stones, which are common and painful. It can also indicate metabolic disorders affecting oxalate metabolism, such as primary hyperoxaluria. Regular monitoring may be needed if you have a history of kidney stones or related conditions.

Short name

24-Hour Urine Oxalate

Frequently asked questions

What causes high oxalate levels in urine?
High urinary oxalate can result from dietary factors (like excessive vitamin C or oxalate-rich foods), certain digestive disorders, or genetic conditions. Lifestyle choices, such as fluid intake and diet, can influence results.
How can I lower my oxalate levels if my test is high?
Your healthcare provider may recommend dietary changes (e.g., reducing oxalate-rich foods like spinach, nuts, or chocolate) and increasing fluid intake. Medications or supplements may also be suggested to help manage levels.
Is there any risk or discomfort with this test?
The test involves collecting urine over 24 hours, which requires careful timing and consistency. There’s no discomfort, but improper collection could lead to inaccurate results. Always follow your provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy