Platinum metabolite concentration in urine (total, 24-hour collection)
This test measures the amount of platinum compounds excreted in your urine over 24 hours, which helps assess exposure to platinum-based chemotherapy drugs like oxaliplatin.
["Helps track platinum drug levels in your body after chemotherapy."]
Key facts at a glance
- LOINC
- 73226-3
- Short code
- Oxaliplatin ind plt IgM SerPl Ql FC
- Synonyms
- Oxaliplatin ind plt IgM SerPl Ql FC
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’re receiving platinum-based chemotherapy, such as oxaliplatin, to monitor how your body is processing the medication. It helps ensure safe dosing and detect potential toxicity early.
What to Expect Before the Test
You’ll collect a 24-hour urine sample starting after your first dose of oxaliplatin. Collect all urine in a container, discarding the first morning urine and saving the rest until the next morning’s first void. Bring the entire sample to your lab for testing.
What the Results Mean
Higher-than-expected levels may indicate excessive platinum exposure, which could cause side effects like kidney damage or nausea. Lower-than-expected levels might suggest poor absorption or metabolism of the drug.
Common Side Effects to Watch For
While this test itself doesn’t cause side effects, platinum chemotherapy can lead to symptoms like nausea, vomiting, or kidney issues. Report any severe symptoms (e.g., pain, swelling, or unusual fatigue) to your doctor.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Monitoring platinum metabolites helps adjust chemotherapy doses to prevent toxicity while ensuring adequate drug levels for effectiveness. Abnormal results may prompt changes in treatment plans or closer monitoring.
Short name
Total urinary platinum metabolites
Frequently asked questions
Why is this test important for my chemotherapy treatment?
Can I drink alcohol before this test?
How often will I need this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy