Oxycodone concentration in urine (24-hour collection)
This test measures the amount of oxycodone, a prescription opioid pain medication, in your urine over a 24-hour period. It helps assess recent exposure or misuse.
["Checks for recent opioid use in your urine over a full day."]
Key facts at a glance
- LOINC
- 19645-1
- Short code
- oxyCODONE CtO Ur Cfm-mCnc
- Synonyms
- oxyCODONE CtO Ur Cfm-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Understanding why your doctor ordered this test can help you feel more prepared and confident about your care.
Your healthcare provider may order this test if you have concerns about opioid use, pain management, or compliance with a medication regimen. It can also be used in workplace drug testing, legal cases, or monitoring for substance use disorders.
The test works by detecting specific markers in your body, giving your doctor clear information about your health.
A urine sample is collected over 24 hours. The sample is then analyzed to detect and measure oxycodone, a controlled substance. The test identifies the presence and quantity of the drug in your system.
A small sample is collected either at the clinic or a lab, and the process is quick, safe, and relatively painless.
You’ll need to collect all urine produced in a 24-hour period in a sterile container. Some facilities provide special containers or instructions to ensure accuracy. Follow your healthcare provider’s or lab technician’s specific guidelines for proper sample handling.
Most people find the test simple and comfortable; you may feel brief discomfort, but it usually goes away quickly.
No special preparation is typically required, but you may be asked to avoid certain medications or substances that could interfere with the test results. Your sample is processed in a lab, and results are usually available within a few days.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Urine Oxycodone (24h)
Frequently asked questions
High levels of oxycodone in urine may indicate recent opioid use, misuse, or non-compliance with prescribed medication. Low or undetectable levels suggest no recent exposure. This test is not diagnostic for addiction but can provide evidence of opioid use for monitoring or legal purposes.
A positive result means oxycodone was detected in your urine during the 24-hour period. This could mean you took the medication as prescribed, used it recreationally, or had exposure through other means. Your healthcare provider will discuss the next steps based on the context and your medical history.
No, diet does not affect this test. However, certain medications or substances (like some antibiotics or herbal supplements) might interfere with urine drug tests in general, but oxycodone-specific interference is rare.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy