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Oxycodone concentration in urine (24-hour collection)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of oxycodone, a prescription opioid pain reliever, in your urine over a 24-hour period. It helps assess drug use, compliance with medication, or potential exposure.

Quick summary

["This test checks for opioid presence in your urine, often used in pain management or substance use evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
14863-5
Short code
oxyCODONE Gast Ql
Synonyms
oxyCODONE Gast Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor your use of oxycodone or other opioids. It could be part of a routine check-up, a follow-up after a prescription change, or as part of a drug screening process, such as before employment, for legal reasons, or to evaluate pain management effectiveness.

What Does the Test Involve?

No special preparation is typically needed, but you may be asked to avoid certain foods or medications that could interfere with the test results. Always follow your healthcare provider’s instructions carefully.

What Are Common Uses?

It may also be used in legal cases, such as determining drug use in personal injury claims or criminal proceedings, or to assess opioid dependence in medical evaluations.

What Might Affect Results?

For example, some medications may increase or decrease the amount of oxycodone detected in your urine, or they might interfere with how the test identifies the drug.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Urine Oxycodone (24h)

Frequently asked questions

How long does it take to get results?
Results are typically available within a few days to a week, depending on the lab’s processing time. Your healthcare provider will contact you once the results are ready, so keep their contact information handy.
What if my results are abnormal?
If your test results show elevated levels of oxycodone, your healthcare provider will discuss them with you. They may recommend adjustments to your medication, further testing, or referrals to specialists if needed. Never assume anything based on test results alone—always talk to your provider.
Can I drink alcohol before this test?
Alcohol itself won’t directly affect the oxycodone test, but it can influence urine concentration and may sometimes interfere with certain lab tests. If your provider has specific instructions, follow them closely. Generally, moderate hydration is encouraged to support proper urine collection.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy