Oxycodone concentration in plasma or serum
This test measures the amount of oxycodone, a prescription opioid pain medication, in your blood. It helps determine your current drug level and whether you’re taking it as prescribed.
["This test helps assess your opioid exposure and potential risks of overdose or dependence."]
Key facts at a glance
- LOINC
- 68543-8
- Short code
- oxyCODONE Mec Cfm-mCnt
- Synonyms
- oxyCODONE Mec Cfm-mCnt
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you’re taking oxycodone regularly, experiencing symptoms like confusion, slow breathing, or unusual drowsiness, or if you’ve been exposed to oxycodone in another way (e.g., accidental ingestion). It can also be used to monitor compliance with treatment or detect misuse.
What Does the Test Involve?
A blood sample is taken from a vein in your arm. The sample is then sent to a lab to measure the oxycodone concentration using a sensitive detection method, often a type of immunoassay or chromatography.
What Should You Expect Before the Test?
No special preparation is usually needed, but avoid eating or drinking anything for at least 8 hours before the test if instructed. If you’re taking other medications, let your provider know to avoid potential interactions.
What Are Common Results?
Results are reported as the concentration of oxycodone in nanograms per milliliter (ng/mL) or micrograms per milliliter (µg/mL). These values can vary based on factors like dosage, metabolism, and time since last dose. Your provider will interpret the results in the context of your medical history and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Oxycodone Level (Plasma/Serum)
Frequently asked questions
What Does a High Level Mean?
What Does a Low Level Mean?
How Often Should This Test Be Done?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy