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Oxycodone and Oxymorphone Concentration in Urine (Drug Screen)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of oxycodone and oxymorphone, two active ingredients in pain medications, in your urine. It helps detect recent use of these opioids.

Quick summary

["This test can help monitor pain management or identify misuse of prescription opioids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91044-8
Short code
oxyCODONE+oxyMORphone Fld Ql Scn
Synonyms
oxyCODONE+oxyMORphone Fld Ql Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for two related compounds: oxycodone and oxymorphone. These substances are found in medications like OxyContin®, Percocet®, and others. Oxycodone is converted in the body into oxymorphone, so both are tracked together to assess overall opioid exposure.

Why It’s Done

Your healthcare provider may order this test if you’re taking opioids for pain, if you’re suspected of opioid misuse, or as part of a broader drug screening (e.g., workplace, legal, or pre-employment). It can also be used to check for recent use before certain procedures.

How the Test Works

A small urine sample is collected and analyzed using a sensitive chemical method (likely high-performance liquid chromatography or immunoassay). This detects even small amounts of these drugs in your system.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain foods or medications that could interfere with results. Follow your provider’s instructions if you’re pregnant, breastfeeding, or have kidney issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate recent opioid use, which could affect pain management, safety during procedures, or legal/employment decisions. Negative results mean these drugs were not detected in your urine at the time of testing. Results may also help assess compliance with prescribed medications or identify potential misuse.

Short name

Urine Drug Panel (Oxycodone/Oxymorphone)

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab and testing method. Your provider will contact you with the final report.
Can I drink water before this test?
Yes, you can drink water as usual unless your provider specifies otherwise. Avoid excessive fluids that might dilute the sample, as this could affect test accuracy.
What if my results are positive?
A positive result means these opioids were detected in your urine. Your provider will discuss next steps, which may include adjusting your medication, further testing, or additional questions about your use. Always follow their guidance for next actions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy