Oxycodone and Oxymorphone Concentration (Serum/Plasma)
This test measures the levels of oxycodone and oxymorphone, two opioid pain medications, in your blood or plasma. These drugs are used to manage moderate to severe pain.
["This test helps monitor your response to opioid pain treatment and detect potential drug misuse or overdose risks."]
Key facts at a glance
- LOINC
- 91032-3
- Short code
- oxyCODONE+oxyMORphone Mec Ql Scn
- Synonyms
- oxyCODONE+oxyMORphone Mec Ql Scn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- screen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’re taking oxycodone or oxymorphone for pain management, if you’ve experienced side effects like drowsiness or confusion, or if you’re suspected of opioid misuse. It can also be part of a broader drug screening, such as for pre-employment, legal, or workplace safety purposes.
What to Expect Before the Test
No special preparation is needed. You may have a blood draw from a vein in your arm or a urine sample collected in a sterile container. If you’re taking blood, you might feel a slight pinch, but it usually doesn’t cause discomfort. If you’re unsure about the test type, ask your provider.
What the Results Mean
Results show the concentration of oxycodone and oxymorphone in your system. High levels may indicate improper use, overdose risk, or recent ingestion. Low levels could suggest poor absorption or medication adherence. Always discuss your results with your healthcare provider.
Common Side Effects or Risks
The test itself is generally safe but may cause mild bruising, soreness, or redness at the injection site if blood is drawn. Urine tests are typically painless. Rarely, allergic reactions can occur, but this is uncommon.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Oxycodone and oxymorphone are potent opioids used to treat pain. Elevated levels in blood or urine can signal misuse, addiction, or overdose. Healthcare providers use these tests to adjust dosages, assess compliance, or identify potential risks of dependence or toxicity. In legal or workplace settings, they may detect unauthorized use.
Short name
Drug Screen (Oxycodone/Oxymorphone)
Frequently asked questions
How long does it take to get results from this test?
Can I drink alcohol before this test?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy