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Oxycodone and Oxymorphone Concentration in Urine (Screening and Confirmation)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of oxycodone and oxymorphone, two active ingredients in pain medications, in your urine. It helps detect recent use of these drugs.

Quick summary

["This test screens for common painkillers that may be in your system, often ordered after suspected misuse or exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91053-9
Short code
oxyCODONE+oxyMORphone Tiss Ql Scn
Synonyms
oxyCODONE+oxyMORphone Tiss Ql Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test gives your healthcare provider important information about your health by measuring specific substances in your body. It is often ordered to help diagnose a medical condition, check how well a treatment is working, or screen for problems before symptoms appear. Your provider will explain the specific reason this test was ordered for you.

Doctors may order this test to check for recent use of oxycodone or oxymorphone—commonly prescribed for pain management. It can be used in medical evaluations, workplace drug testing, or after suspected overdose or accidental exposure.

Before the test, your care team will give you specific instructions, which may include fasting for a certain number of hours, avoiding certain foods or medications, or drinking plenty of water. Tell your provider about any medications, supplements, or allergies you have. Plan to arrive a few minutes early with your insurance card and a list of your current medications.

No special preparation is needed. You’ll provide a urine sample in a private area. If testing for recent use, results may reflect exposure within hours to days, depending on the drug’s half-life in your body.

Your results will show whether your values fall within the normal reference range for this test. A result within range usually means no problem was found, while an out-of-range result does not always mean you are ill; it may simply call for repeat testing or closer monitoring. Your healthcare provider will review the results with you, explain what they mean in the context of your overall health, and discuss any next steps.

Positive results indicate the presence of oxycodone or oxymorphone in your urine. The concentration can help determine the timing of use (e.g., acute vs. chronic exposure). False positives may occur with certain medications or contaminants.

This test is commonly used to help diagnose conditions, monitor ongoing health problems, and guide treatment decisions. Keep in mind that no single test tells the whole story. Results can be affected by medications, diet, stress, and other factors, and false positive or false negative results can occur. Your provider interprets your results alongside your symptoms, medical history, and other testing.

This test is most useful for detecting recent drug use, not long-term storage. It’s not a definitive test for addiction but may flag potential misuse. False positives can occur with other substances or medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Urine Drug Screen (Oxycodone/Oxymorphone)

Frequently asked questions

This test helps identify exposure to oxycodone or oxymorphone, which can guide treatment decisions, monitor compliance with medication regimens, or assess risk in medical or legal contexts. High levels may indicate misuse, overdose risk, or accidental ingestion.
Most results are available within a few days, although some tests are ready the same day while others may take a week or longer. Your provider's office or patient portal will notify you when your results are ready, and you can always call the office to ask about the status of your test.
Results are typically available within 1–3 business days, depending on the lab. Urgent cases may receive results sooner. Follow-up with your healthcare provider if you have concerns about your results.
In most cases, yes. Drinking plain water before the test is encouraged because it keeps you hydrated and makes a blood draw easier. However, if your instructions include fasting, avoid coffee, juice, and other beverages until the test is complete, and follow any specific guidance your provider gave you. When in doubt, call your care team for clarification.
Yes, you can drink water as usual unless instructed otherwise. Avoid excessive fluids that might dilute the sample if timing is critical for interpretation.
If prescribed, inform your doctor or lab technician about current medications. They may adjust testing parameters to avoid false negatives or positives. Always follow your prescribed dosing schedule.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy