Oxycodone and Oxymorphone Urine Drug Screening (Quantitative)

What This Test Measures

The test detects two related compounds: oxycodone and oxymorphone. Both are opioids derived from the same chemical structure but may appear differently in drug screens. Oxycodone is the primary active ingredient in many prescription pain relievers, while oxymorphone is a metabolite formed in the body from oxycodone.

Why It’s Done

Healthcare providers may order this test to evaluate recent use of oxycodone-based medications, assess compliance with treatment plans, or screen for substance use—especially if you’re prescribed these drugs or have concerns about misuse.

Sample Collection and Process

A urine sample is collected in a sterile container. The test typically uses a high-performance liquid chromatography (HPLC) method to identify and quantify these substances. Results are reported as mass concentration in micrograms per milliliter (µg/mL).

Interpreting Your Results

Results are qualitative (positive/negative) or quantitative, depending on the lab’s protocol. A positive result indicates the presence of oxycodone or oxymorphone, but it does not specify the exact amount or duration of use. Follow-up testing may be needed for confirmation.