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Drug Concentration Screening Test for Oxycodone and Oxymorphone (Urine)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of oxycodone and oxymorphone, two pain medications, in your urine. It helps determine if you’ve used these drugs recently.

Quick summary

["This test screens for common opioids in urine, often used for monitoring substance use or detecting recent medication use."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58430-0
Short code
oxyCODONE+oxyMORphone Ur Ql Scn
Synonyms
oxyCODONE+oxyMORphone Ur Ql Scn
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking oxycodone or oxymorphone regularly, if you’re suspected of using opioids, or as part of a routine check for substance use. It can also be used in workplace drug testing or before certain surgeries.

What to Expect Before the Test

No special preparation is needed. You’ll be asked to provide a urine sample in a clean container. If you’re using certain medications or supplements, let your provider know, as they may affect results.

What the Test Measures

The test detects the chemical compounds oxycodone and oxymorphone in your urine. These are active ingredients in prescription painkillers. A positive result means these drugs (or their metabolites) were found in your urine.

How the Test Results Are Interpreted

Results are typically reported as positive or negative. A positive result indicates recent use of these medications, but it doesn’t always show how much was taken or for how long. Follow-up testing (like a confirmatory urine drug screen) may be needed for further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Drug Screen (Oxycodone/Oxymorphone)

Frequently asked questions

What does a positive result mean?
A positive result means your urine contained oxycodone or oxymorphone, indicating recent use of these medications. This could be due to prescribed use, misuse, or accidental exposure. Your healthcare provider will discuss next steps based on the context.
Can false positives or negatives occur?
Yes, false positives are rare but possible, especially with certain medications or supplements. False negatives can happen if the test isn’t done soon enough after use. If your results are unclear, follow-up testing may be recommended.
How long after taking the medication might this test still show a positive result?
Oxycodone and oxymorphone can be detected in urine for several days after use, depending on the dose and individual metabolism. For example, a single dose may show up for 2–3 days, while chronic use could extend detection longer. Always follow your provider’s guidance for interpretation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy