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Oxycodone Mass Concentration in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of oxycodone, a prescription opioid pain medication, in your blood. It helps assess drug levels for monitoring treatment or detecting exposure.

Quick summary

["This test helps doctors track how your body processes oxycodone and ensures safe dosing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3893-5
Short code
oxyCODONE SerPl-mCnc
Synonyms
oxyCODONE SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking oxycodone for pain management, experiencing symptoms like confusion, slowed breathing, or overdose, or if you’re suspected of drug exposure. It can also be used in medical monitoring, such as during detoxification or in cases of suspected abuse.

What to Expect Before the Test

No special preparation is needed. You may be asked to fast before the draw, but this isn’t always required. Bring any medications you’re taking to your appointment.

How the Test Is Done

A healthcare professional will collect a blood sample from a vein in your arm using a small needle. The blood will be sent to a lab for analysis.

What the Results Mean

Results show the concentration of oxycodone in your blood. Higher levels may indicate recent use, improper dosing, or potential toxicity. Your doctor will interpret results based on your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Oxycodone Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time.
Can I stop taking oxycodone before this test?
Only follow your doctor’s instructions. Stopping oxycodone abruptly can cause withdrawal symptoms or harm. If you’re unsure, ask your provider before the test.
Does this test detect other opioids?
This test specifically measures oxycodone only. If you’re concerned about other opioids, your doctor may order a broader drug screen.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy