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Oxycodone Substance Concentration in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of oxycodone, a prescription pain medication, in your blood. It helps doctors assess your current drug level and monitor your response to treatment.

Quick summary

["This test helps track how much oxycodone is in your blood, which is important for managing pain safely and avoiding overdose."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13576-4
Short code
oxyCODONE SerPl Ql
Synonyms
oxyCODONE SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking oxycodone regularly, experiencing side effects, or if you’re suspected of drug misuse or overdose. It helps ensure safe dosing and prevents complications like respiratory depression or addiction.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. If you’re on a long-term opioid regimen, your provider may schedule this test periodically to monitor levels.

What the Results Mean

Results show the concentration of oxycodone in your blood. Higher levels may indicate overdose risk, while lower levels could suggest inadequate pain control. Your provider will interpret results based on your medical history and current needs.

Common Reasons for Testing

Doctors may test for oxycodone to confirm overdose, evaluate pain management effectiveness, check for drug interactions, or screen for misuse (e.g., in addiction treatment). It’s also used in legal cases or workplace drug testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Oxycodone is a potent opioid that can cause serious side effects, including drowsiness, slowed breathing, or addiction. High levels may lead to coma or death. Regular monitoring helps balance pain relief with safety. Always follow your provider’s instructions for dosing and avoid mixing with other central nervous system depressants.

Short name

Oxycodone Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab and insurance. Your healthcare provider will contact you once they have the results.
What if my results are outside the expected range?
If your oxycodone level is unusually high or low, your doctor will review your symptoms, medication history, and other tests to determine the best next steps. They may adjust your dose or investigate other causes.
Can I eat or drink before this test?
You can eat and drink normally before the test, as it’s a blood draw with no dietary restrictions. However, inform your provider if you’re on any medications that might affect blood tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy