Oxygenated hemoglobin mass fraction in red blood cells (HbO₂ mass fraction)
This test measures the proportion of oxygen-bound hemoglobin within your red blood cells, which helps assess how well oxygen is being delivered to your tissues.
["Helps evaluate oxygen transport efficiency in your blood."]
Key facts at a glance
- LOINC
- 2715-1
- Short code
- OxyHgb MFr BldC
- Synonyms
- OxyHgb MFr BldC
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Measuring?
Oxygenated hemoglobin (HbO₂) is the form of hemoglobin that carries oxygen from your lungs to your body’s tissues. This test quantifies the mass fraction of HbO₂ in your red blood cells, providing insight into how effectively your blood is transporting oxygen. While not a standalone diagnostic for oxygen-related conditions, it can be part of broader evaluations for respiratory, cardiovascular, or blood-related disorders.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like shortness of breath, fatigue, or signs of poor oxygenation (e.g., blue lips or skin). It may also be used in monitoring conditions such as anemia, chronic obstructive pulmonary disease (COPD), or other respiratory or circulatory issues where oxygen transport is a concern.
How Is the Test Performed?
A small blood sample is drawn from a vein, typically in your arm. The sample is processed to measure the oxygen-bound hemoglobin content. Results are usually available within a few days, depending on lab turnaround times.
What Do the Results Mean?
Interpretation depends on clinical context and may not provide standalone reference ranges. Elevated levels could suggest efficient oxygen delivery, while lower levels might indicate reduced oxygenation capacity. Your provider will discuss findings in relation to your symptoms and medical history.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HbO₂ mass fraction
Frequently asked questions
How is this test different from a standard hemoglobin A1c test?
What are the typical reference ranges for this test?
Can this test be done on urine or other body fluids?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy