Skip to content

Oxygenated hemoglobin mass fraction in red blood cells (HbO₂ mass fraction)

Published: August 9, 2026Updated: August 16, 2026

This test measures the proportion of oxygen-bound hemoglobin within your red blood cells, which helps assess how well oxygen is being delivered to your tissues.

Quick summary

["Helps evaluate oxygen transport efficiency in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2715-1
Short code
OxyHgb MFr BldC
Synonyms
OxyHgb MFr BldC
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Oxygenated hemoglobin (HbO₂) is the form of hemoglobin that carries oxygen from your lungs to your body’s tissues. This test quantifies the mass fraction of HbO₂ in your red blood cells, providing insight into how effectively your blood is transporting oxygen. While not a standalone diagnostic for oxygen-related conditions, it can be part of broader evaluations for respiratory, cardiovascular, or blood-related disorders.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like shortness of breath, fatigue, or signs of poor oxygenation (e.g., blue lips or skin). It may also be used in monitoring conditions such as anemia, chronic obstructive pulmonary disease (COPD), or other respiratory or circulatory issues where oxygen transport is a concern.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The sample is processed to measure the oxygen-bound hemoglobin content. Results are usually available within a few days, depending on lab turnaround times.

What Do the Results Mean?

Interpretation depends on clinical context and may not provide standalone reference ranges. Elevated levels could suggest efficient oxygen delivery, while lower levels might indicate reduced oxygenation capacity. Your provider will discuss findings in relation to your symptoms and medical history.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbO₂ mass fraction

Frequently asked questions

How is this test different from a standard hemoglobin A1c test?
This test focuses specifically on oxygen-bound hemoglobin in red blood cells, unlike an A1c test, which measures average blood sugar levels over time. Both are blood tests but serve distinct purposes in diagnosing different health conditions.
What are the typical reference ranges for this test?
Reference ranges for oxygenated hemoglobin mass fraction can vary by lab and individual factors. Since this is a qualitative measurement of mass fraction rather than a fixed numeric value, results are interpreted in the context of your clinical situation rather than a single range.
Can this test be done on urine or other body fluids?
No, this test requires a blood sample to measure oxygen-bound hemoglobin in red blood cells. It is not performed on urine or other fluids.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy