Oxymorphone concentration in urine (24-hour collection)

Why This Test Is Done

Your healthcare provider may order this test if you’re taking oxymorphone (a controlled opioid) for pain management, or if there’s concern about misuse, overdose risk, or compliance with treatment plans. It may also be used in workplace drug testing, legal cases, or monitoring substance use disorders.

What to Expect Before the Test

You’ll collect a 24-hour urine sample starting from midnight one day and ending midnight the next. Drink plenty of water to help flush out the medication naturally. Avoid certain foods, drinks, or medications that could interfere with results (like grapefruit juice or certain supplements). Follow your provider’s instructions carefully.

What Happens During the Test

You’ll provide a sealed container with your 24-hour urine sample. The lab will analyze the urine for oxymorphone levels using a sensitive detection method. No special preparation is needed beyond collecting the sample correctly.

What the Results Mean

Results show the total amount of oxymorphone excreted in your urine over 24 hours. Higher levels may indicate recent use, improper dosing, or potential misuse. Your provider will interpret results in the context of your medical history, symptoms, and treatment goals.