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Plasma or serum protein mass concentration (e.g., albumin, globulin, or other protein fractions)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, often broken down into different types like albumin and globulins. It helps assess how well your proteins are functioning in your body.

Quick summary

["Protein levels can reveal clues about kidney function, liver health, or immune system status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18249-3
Short code
pABA SerPl-mCnc
Synonyms
pABA SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if they suspect conditions like kidney disease, liver problems, or infections. It can also be used to monitor chronic conditions such as heart disease or certain autoimmune disorders.

What to Expect Before the Test

You’ll likely have a simple blood draw, usually from a vein in your arm. No special preparation is needed unless instructed otherwise. The test may be done at a lab or during a routine doctor’s visit.

What the Results Mean

Results show the total protein mass in your blood, which can help identify imbalances. For example, low protein might suggest malnutrition or liver/kidney issues, while high levels could indicate dehydration or certain cancers.

Common Conditions Monitored

This test helps diagnose or track conditions like chronic kidney disease, liver cirrhosis, or conditions affecting protein synthesis (e.g., malnutrition). It can also support evaluations for inflammatory diseases or infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein levels can signal underlying health issues, such as fluid imbalances, organ dysfunction, or immune system problems. Your doctor will interpret results in the context of your medical history and symptoms.

Short name

Protein Profile (Mass Concentration)

Frequently asked questions

What does a protein profile test measure?
It measures the total mass concentration of proteins in your blood, including albumin, globulins, and other proteins. This helps assess overall protein status and identify potential imbalances.
How is this test different from a standard blood test?
Unlike standard blood tests (e.g., complete blood count), this test focuses specifically on protein amounts rather than cells or other substances. It provides insight into protein function and health.
Can fasting affect this test?
Fasting may not typically affect protein levels measured this way, but your doctor may still advise fasting for other related tests. Always follow their specific instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy