Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding) for Urinary Protein/Albumin Ratio (24-Hour Collection)

Why This Test Is Done

Your doctor may order this test if you have symptoms like swelling, frequent urination, or unexplained weight changes. It’s also used to monitor kidney function in people with diabetes, high blood pressure, or a history of kidney problems. Some tests may be done before kidney procedures or to check for proteinuria (protein in urine).

What to Expect Before the Test

For a 24-hour urine collection, you’ll collect all urine for a full day, typically starting after your first morning urine. Drink plenty of water but avoid foods that might affect urine color (like beets or berries). Follow your doctor’s instructions carefully to ensure accurate results.

How the Test Works

Your urine is tested for both total protein and albumin using a dye called bromocresol green. The ratio helps identify if protein is being lost in urine, which can indicate kidney damage or other health concerns.

What the Results Mean

Higher-than-normal ratios may suggest kidney problems, such as glomerulonephritis, diabetic nephropathy, or other conditions causing protein leakage. Lower ratios may indicate normal kidney function or conditions like liver disease (where protein is retained). Always discuss results with your doctor.