Escherichia coli (E. coli) bacterial DNA in urine by probe-based nucleic acid amplification test

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urination, pain or burning during urination, cloudy or strong-smelling urine, or if you’ve been diagnosed with a urinary tract infection (UTI) and symptoms persist or recur. It may also be used to confirm or monitor suspected infections in certain clinical settings.

How the Test Works

The test uses a specialized probe to detect genetic material (DNA) from *E. coli* bacteria in your urine sample. This method is highly sensitive and can identify the presence of the bacteria even if they are not growing in the lab, which helps confirm infection earlier than traditional culture methods.

Sample Collection and Preparation

You will provide a urine sample, typically collected in a clean container. The sample is then processed to extract DNA, which is analyzed for the presence of *E. coli* genetic markers. No special preparation is needed, but avoid urinating right before the test if possible.

What to Expect After the Test

Results are usually available within a few days. If the test is positive, it suggests the presence of *E. coli* in your urine, which may require treatment with antibiotics. Follow-up may include additional tests or monitoring to ensure proper recovery.