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Protein Electrophoresis, Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood serum, helping identify abnormalities in protein distribution.

Quick summary

["Protein electrophoresis helps diagnose conditions like multiple myeloma, liver disease, or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29497-5
Short code
PA IgG Bld Ql FC
Synonyms
PA IgG Bld Ql FC
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins based on size and charge, revealing distinct bands corresponding to albumin, globulins (including alpha, beta, and gamma fractions), and other proteins. This helps detect imbalances that may signal underlying health issues.

Why Is This Test Done?

Your healthcare provider may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or changes in kidney/liver function. It’s also used in screening for conditions like multiple myeloma, amyloidosis, or chronic inflammatory diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The serum (liquid part after clotting) is separated and analyzed using an electric field to separate proteins. No special preparation is needed, but fasting may be advised depending on your specific order.

Common Conditions Evaluated

This test can highlight conditions like monoclonal gammopathy (e.g., multiple myeloma), hypoalbuminemia (low albumin), or dysproteinemias (abnormal protein patterns). It may also help monitor treatment responses in chronic diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Protein Electrophoresis

Frequently asked questions

What Does an Abnormal Result Mean?
Abnormal bands or shifts in protein patterns may indicate conditions affecting protein synthesis, storage, or breakdown. For example, a spike in one protein band could suggest a monoclonal protein (seen in myeloma), while low albumin might point to liver or kidney disease. Always discuss results with your provider.
How Long Does It Take to Get Results?
Results are typically available within 24–48 hours, depending on lab processing. Follow-up may include additional tests or consultations to interpret findings.
Do I Need to Fast Before This Test?
Fasting is usually not required, but check with your provider if your order specifies otherwise. Hydration and comfort are the priority—let your healthcare team know if you experience dizziness or pain during the draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy