Skip to content

Protein Electrophoresis (Serum) with Qualitative Analysis for Albumin and Globulin Bands

Published: August 9, 2026Updated: August 17, 2026

This test measures the distribution of different protein types in your blood serum, including albumin and globulin fractions, often used to assess protein balance or detect abnormalities like infections, inflammation, or certain blood disorders.

Quick summary

["Helps identify protein patterns that may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
108983-8
Short code
p-ANCA atypical Msmt Ser
Synonyms
p-ANCA atypical Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test separates proteins in your blood into distinct bands based on size and charge. Key components include albumin (the most abundant protein, typically appearing as a dense band near the anode) and globulins (divided into alpha, beta, and gamma fractions, which may vary with conditions like infections or immune disorders).

Why It’s Ordered

Doctors may recommend this test to diagnose conditions like multiple myeloma, liver disease, kidney problems, or chronic infections. It can also help monitor treatment progress or screen for hidden protein abnormalities.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The serum (liquid part after clotting) is then analyzed in a lab to separate proteins via electrophoresis, a process that sorts them by size and charge.

Common Uses and Clinical Contexts

This test is often used alongside other blood tests to evaluate protein metabolism, detect monoclonal gammopathies (unusual protein spikes), or assess conditions affecting protein synthesis or breakdown.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns can indicate systemic diseases, such as immune system disorders (e.g., multiple myeloma), liver or kidney dysfunction, or chronic inflammation. For example, elevated gamma globulins may signal autoimmune diseases, while a shift in albumin could reflect malnutrition or liver issues.

Short name

Serum Protein Electrophoresis (Qualitative)

Frequently asked questions

What does a ‘qualitative’ result mean?
A qualitative result provides a descriptive pattern (e.g., ‘normal distribution,’ ‘monoclonal spike,’ or ‘globulin predominance’) rather than exact measurements. This helps identify broad trends without precise numbers.
How long will I need to fast for this test?
No fasting is required for this test, as it measures serum proteins without dietary influence. However, inform your doctor about any medications or supplements you’re taking, as they may affect results.
Can this test detect early-stage diseases?
While it can reveal protein abnormalities linked to diseases like multiple myeloma or liver disease, it’s not always definitive on its own. Doctors may order additional tests (e.g., urine protein screening or further bloodwork) for a full diagnosis.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy