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Serum or Plasma Protein Electrophoresis (Bromocresol Green)

Published: August 9, 2026Updated: August 17, 2026

This test measures the distribution of proteins in your blood, separated by size and charge, using a dye called bromocresol green. It helps identify abnormalities in protein patterns that may suggest conditions like multiple myeloma, liver disease, or other disorders.

Quick summary

["This test helps diagnose and monitor conditions affecting protein balance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
17357-5
Short code
p-ANCA Ser Ql IF
Synonyms
p-ANCA Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Does This Test Measure?

The test separates blood proteins into fractions, including albumin, alpha-globulins, beta-globulins, and gamma-globulins. Each fraction may contain different proteins like immunoglobulins, enzymes, or other substances that can be affected by disease.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if they suspect conditions like multiple myeloma (a cancer of plasma cells), chronic liver disease, kidney disease, or other disorders that alter protein production or distribution in the blood.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The serum or plasma is then separated and mixed with bromocresol green dye. An electric current is applied to separate proteins based on their size and charge, creating bands that reflect protein concentration.

What Does the Test Result Mean?

Results show the relative amounts of each protein fraction. Abnormal patterns, such as increased or decreased bands, may indicate specific health concerns. Your doctor will interpret the results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is crucial for diagnosing and managing conditions that affect protein synthesis, storage, or breakdown. For example, an abnormal electrophoresis pattern may reveal monoclonal gammopathy (a hallmark of multiple myeloma) or signs of liver or kidney dysfunction. Early detection can guide treatment decisions.

Short name

Bromocresol Green Protein Electrophoresis

Frequently asked questions

What does a bromocresol green electrophoresis test measure exactly?
This test measures the concentration and distribution of different protein fractions in your blood using bromocresol green dye to visualize them. It helps identify potential abnormalities in protein patterns that may signal underlying health conditions.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on lab processing times and your healthcare provider’s workflow. Follow-up with your doctor to discuss findings.
Can I eat or drink anything before this test?
No special diet or preparation is needed for this test. However, inform your doctor about any medications or supplements you’re taking, as they may affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy