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Pancreatic Amylase and Lipase Screening Test (Serum)

Published: August 9, 2026Updated: August 17, 2026

This test measures levels of enzymes produced by your pancreas to help check for inflammation, blockages, or damage.

Quick summary

["Assesses pancreatic health by detecting key digestive enzymes in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
32787-4
Short code
p-ANCA Titr Ser
Synonyms
p-ANCA Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like abdominal pain, nausea, vomiting, or unexplained weight loss. It’s also used to monitor conditions like pancreatitis, pancreatic cancer, or chronic pancreatitis. Sometimes, it’s part of a broader evaluation for digestive issues or after trauma to the abdomen.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if your lab requires it. Bring any medications you’re currently taking, as some may affect results. Avoid heavy meals or alcohol before testing.

What Happens During the Test

A healthcare provider will draw blood from a vein in your arm. The process is quick and usually painless. You may feel a slight pinch, but the area will numb quickly. The blood sample is sent to a lab for analysis.

What the Results Mean

Higher-than-normal levels of these enzymes may indicate pancreatic issues, such as inflammation (pancreatitis), blockages, or tumors. Lower-than-normal levels might suggest pancreatic insufficiency or other conditions. Results are interpreted by your doctor in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pancreatic Enzyme Screen

Frequently asked questions

What causes elevated pancreatic enzymes?
Common causes include acute pancreatitis (often from heavy alcohol use, gallstones, or severe infections), pancreatic tumors, or blockages in the pancreatic duct. Other triggers may include severe abdominal trauma, certain medications, or metabolic disorders.
How long do results usually take?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can I take my medications before the test?
Yes, but inform your doctor or lab staff about all medications, including over-the-counter drugs and supplements. Some medications (like steroids or certain painkillers) may affect enzyme levels, so they should be noted for accuracy.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy