Pancreatic Islet Cell Antibody (Serum) by Immunoassay
This test measures antibodies that may indicate an autoimmune response targeting the cells in your pancreas responsible for producing insulin. It’s often used to help diagnose conditions like type 1 diabetes or other autoimmune pancreatic disorders.
["This test helps identify potential autoimmune issues affecting insulin production."]
Key facts at a glance
- LOINC
- 13927-9
- Short code
- Panc Islet Cell Ab Titr Ser
- Synonyms
- Panc Islet Cell Ab Titr Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained weight loss, frequent thirst, excessive urination, or unexplained fatigue. It may also be used in cases where type 1 diabetes is suspected but blood glucose tests alone are inconclusive.
What to Expect During the Test
A blood sample will be taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The sample is then sent to a lab for analysis using an immunoassay method to detect specific antibodies.
Sample Collection and Preparation
The test uses serum from a blood sample. No special preparation is needed, but fasting may be advised depending on your healthcare provider’s instructions.
What the Results Mean
Positive results suggest the presence of antibodies against pancreatic islet cells, which may indicate an autoimmune condition. However, results alone don’t confirm a diagnosis; they’re typically used alongside other tests and clinical findings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results for pancreatic islet cell antibodies are strongly associated with type 1 diabetes and other autoimmune pancreatic disorders. Early detection can help guide treatment plans, such as monitoring for insulin deficiency or managing symptoms before they become severe.
Short name
Islet Cell Antibody (Serum)
Frequently asked questions
What does a positive result mean for my health?
Will I need to change my diet or lifestyle based on this test?
Can this test be done at home, or do I need a lab visit?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy