: Pancreatic Islet Cell Antibody IgG, Serum, Qualitative
: This test looks for IgG antibodies that target pancreatic islet cells, the insulin-producing cells of the pancreas. It is used as an aid in evaluating autoimmune diabetes, including type 1 diabetes.
[": A positive result suggests an autoimmune response against pancreatic islet cells and is interpreted by a clinician alongside symptoms, glucose testing, and other autoantibodies."]
Key facts at a glance
- LOINC
- 33563-8
- Short code
- Panc Islet Cell IgG Ser-aCnc
- Synonyms
- Panc Islet Cell IgG Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What This Test Measures
: The test detects IgG-class autoantibodies that recognize proteins in pancreatic islet cells. These antibodies are markers of an immune response directed at the insulin-producing beta cells, which can contribute to loss of insulin secretion over time.
: Why It May Be Ordered
: A clinician may order this test when autoimmune diabetes is suspected, when diabetes has an unusual or rapid onset, or when distinguishing type 1 diabetes from other forms of diabetes. It may also be used in family screening or research contexts.
: How the Sample Is Collected
: A blood sample is drawn from a vein, typically from the arm, and the serum is separated for analysis. Preparation instructions are usually minimal, but follow any directions given by your clinician or laboratory.
: How to Interpret Results
: Results are generally reported as positive or negative. A positive result indicates that islet cell antibodies were detected, but it does not by itself confirm a diagnosis; a negative result does not completely rule out autoimmune diabetes. Results should be interpreted with other clinical and laboratory findings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
: Islet cell autoantibodies are associated with type 1 diabetes and other autoimmune conditions. Their presence can support clinical assessment but must be integrated with glucose measurements, symptoms, other diabetes autoantibody tests, and the overall clinical picture; no single antibody result establishes or excludes a diagnosis on its own.
Short name
: Islet Cell Antibodies IgG
Frequently asked questions
: Does a positive result mean I definitely have diabetes?
: Can this test tell type 1 from type 2 diabetes?
: Do I need to fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy