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Paroxetine and Creatinine, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures paroxetine in urine along with creatinine, which can help account for urine dilution when interpreting drug levels.

Quick summary

["This test can help clinicians evaluate paroxetine exposure and whether urine concentration may affect the result."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72785-9
Short code
PARoxetine/Creat Ur
Synonyms
PARoxetine/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of paroxetine, an antidepressant medicine, in a urine sample. Creatinine is measured at the same time to help assess how concentrated the urine is.

Why might I need this test?

A clinician may order it to monitor paroxetine exposure, check medication adherence, or investigate possible effects of drug interactions or reduced drug clearance. The result is interpreted together with dose, timing, symptoms, and other clinical information.

How is the test performed?

A urine specimen is collected and analyzed by the laboratory to determine the paroxetine and creatinine amounts. Depending on the laboratory method, the results may be reported individually or as a urine paroxetine-to-creatinine ratio.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory, including whether a first-morning or timed urine sample is required. Record when you last took paroxetine, and do not change or stop your medication without discussing it with your clinician.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher urine paroxetine result may reflect recent dosing, accumulation, reduced medication clearance, or an interaction with another medicine. A lower result may occur when a dose was missed or the specimen was collected a long time after dosing. Urine creatinine helps clinicians consider how dilute or concentrated the specimen is, but results should not be interpreted in isolation.

Short name

Urine paroxetine and creatinine

Frequently asked questions

Does this test show whether paroxetine is working?
Not by itself. The result can provide information about drug exposure, but treatment effectiveness is assessed using symptoms, side effects, and the overall clinical picture.
Why is creatinine measured with urine paroxetine?
Urine can vary greatly in concentration. Creatinine helps account for urine dilution so that the paroxetine result can be interpreted more reliably.
Can I take paroxetine before providing the urine sample?
Do not skip or change a prescribed dose unless your clinician instructs you to. Tell the healthcare provider when you last took paroxetine because timing can affect the result.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy