Protein Electrophoresis, Serum (Qualitative)
This test measures the different types of proteins in your blood serum using electrophoresis, a method that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or kidney problems."]
Key facts at a glance
- LOINC
- 74452-4
- Short code
- PDW BldCo Auto
- Synonyms
- PDW BldCo Auto
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Is Protein Electrophoresis Used For?
Protein electrophoresis helps doctors detect and monitor conditions by analyzing how proteins move through a gel under an electric field. This can reveal unusual protein bands that might indicate diseases affecting protein production, such as certain cancers or metabolic disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The serum portion is then separated and placed on a gel. An electric current is applied to separate proteins by size and charge, creating distinct bands. These bands are later examined under light to identify any abnormal patterns.
Preparation and Sample Collection
No special preparation is needed for this test. You may eat and drink normally before your blood draw. If you have a history of bleeding disorders or are on blood thinners, inform your healthcare provider beforehand.
Possible Results and Interpretation
Results show different protein bands, including albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal bands or patterns may suggest conditions like multiple myeloma (excess monoclonal proteins), liver disease (altered albumin levels), or kidney disease (proteinuria). Your doctor will interpret the results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Protein electrophoresis is crucial for diagnosing and managing conditions such as multiple myeloma, where abnormal proteins (M proteins) appear. It can also identify liver or kidney dysfunction, infections, or inflammatory diseases by revealing shifts in protein composition. Early detection improves treatment planning and patient outcomes.
Short name
Serum Protein Electrophoresis
Frequently asked questions
Why might my doctor order this test?
What are the common symptoms or conditions this test helps diagnose?
How long does it take to get results from this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy