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: Peptide YY, Serum or Plasma, by Electrophoresis (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of peptide YY, a hormone released by the gut that helps regulate appetite and digestion, in a sample of serum or plasma.

Quick summary

[": Peptide YY testing is a specialized hormone measurement used mainly in research and selected digestive evaluations rather than routine care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49858-4
Short code
Peptide YY SerPl-mCnc
Synonyms
Peptide YY SerPl-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Peptide YY?

: Peptide YY (PYY) is a hormone produced mainly by cells in the lower intestine. It is released after eating and signals feelings of fullness, helping to regulate appetite and the movement of food through the digestive tract.

: How the Test Is Done

: A blood sample is drawn from a vein, usually in your arm, and the serum or plasma is separated for analysis. Because hormone levels can shift with eating, your care team may ask you to fast or to collect the sample at a specific time.

: What the Results Mean

: Results are reported as a mass concentration and are interpreted alongside your symptoms, other hormone tests, and your medical history. There is no single universal cutoff, so your provider will explain what your value means in your specific situation.

: Why It Might Be Ordered

: This test is used most often in specialized or research settings to study appetite regulation or certain digestive and bowel conditions. It is not a routine screening test, and your provider will explain why it is being requested.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Peptide YY

Frequently asked questions

: Do I need to fast before this test?
: Fasting requirements vary because PYY changes with food intake. Follow the specific instructions given by your provider or laboratory.
: Can I interpret my peptide YY result on my own?
: No. Peptide YY is a specialized measurement without a single standardized normal range, so results should be reviewed by your healthcare provider alongside your symptoms and other findings.
: Is this a common test?
: No. Peptide YY testing is uncommon and is used mainly in specialized or research settings rather than as part of routine blood work.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy