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Phenothiazine metabolites in plasma (total, including primary and secondary metabolites)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain breakdown products of phenothiazine medications, which are used to treat conditions like schizophrenia or nausea. Levels may help assess drug effectiveness or side effects.

Quick summary

["This test helps monitor phenothiazine drug levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73211-5
Short code
Perphenazine ind plt IgG SerPl Ql FC
Synonyms
Perphenazine ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking phenothiazine medications, such as prochlorperazine or promethazine. It helps ensure the drug is at an appropriate level to manage symptoms while minimizing side effects. This is particularly important if you’re taking these drugs long-term or at high doses.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm, similar to other routine blood tests. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are not typically provided as a single number but rather as a qualitative or semi-quantitative assessment of metabolite presence. High levels may indicate overdose or improper metabolism, while low levels could suggest insufficient drug concentration. Your provider will interpret results in the context of your symptoms and medication regimen.

Possible Side Effects or Risks

The most common risk is mild discomfort at the needle site, such as bruising or slight pain. Rarely, blood tests can cause allergic reactions or infections, though these are uncommon. If you experience severe pain, swelling, or signs of infection (like fever), contact your provider immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated levels of phenothiazine metabolites may signal toxicity, particularly in overdose situations or in patients with impaired liver function. These drugs can also cause side effects like drowsiness, low blood pressure, or neurological issues. Monitoring metabolite levels helps balance therapeutic benefits with potential risks, especially in patients with kidney or liver conditions.

Short name

Phenothiazine drug levels

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I stop taking my phenothiazine medication before this test?
No, you should not stop taking your medication without consulting your provider first. This test is used to monitor your current drug levels, and abrupt changes could affect test accuracy or your health.
What if my results are outside the expected range?
If your results are abnormal, your provider will review them with you and may adjust your medication dose, treatment plan, or monitor you more closely. This could include additional tests or closer follow-up with your psychiatrist or doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy