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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71528-4
Short code
PERSONNELJOBDESCRIPTION
Synonyms
—
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
esrd
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of inflammation, monitor chronic conditions (such as arthritis or heart disease), or evaluate responses to treatments. It can also help diagnose infections or other inflammatory conditions.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic or liver assessment. Avoid strenuous activity or aspirin/ibuprofen 24 hours prior, as they can affect results.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick. The blood sample is sent to a lab for analysis.

What the Results Mean

Higher-than-normal CRP levels may indicate inflammation, infections, or other health issues. Lower levels suggest reduced inflammation. Your results will be compared to your clinical picture and other tests for accurate interpretation.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker for systemic inflammation and is used broadly to assess risk for cardiovascular disease, guide treatment decisions in autoimmune disorders, or monitor disease activity in conditions like rheumatoid arthritis or sepsis.

Short name

CRP (Serum/Plasma)

Frequently asked questions

How long does it take to get my CRP test results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow-up with your provider to discuss findings.
Can diet or exercise affect CRP levels?
Dietary factors (e.g., Mediterranean diet) and physical activity can influence CRP levels, but results are interpreted in the context of your overall health. Avoiding stress or inflammation-inducing foods may help, but results alone don’t diagnose conditions.
Is CRP always elevated in infections?
No. While CRP rises in infections, it can also increase with other inflammatory conditions (e.g., autoimmune diseases) or stress. Your provider will consider symptoms, other tests, and medical history for diagnosis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy