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Serum or plasma mass concentration of gamma-glutamyl carboxypeptidase (GGC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of gamma-glutamyl carboxypeptidase, an enzyme involved in the metabolism of certain amino acids. It may be ordered to assess liver function or detect conditions affecting amino acid processing.

Quick summary

["This test helps evaluate liver health and metabolic enzyme activity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2786-2
Short code
PG Amn-mCnc
Synonyms
PG Amn-mCnc
Category
glucose
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to liver disease, amino acid metabolism disorders, or suspected enzyme deficiencies. It could also be part of a broader evaluation for unexplained biochemical imbalances.

What to Expect Before the Test

No special preparation is typically required. You may fast or take certain medications as directed by your provider. Blood is drawn from a vein in your arm, similar to other routine blood tests.

What the Results Mean

Results are interpreted by your healthcare provider based on your medical history and symptoms. Abnormal levels may suggest liver dysfunction, genetic enzyme disorders, or other metabolic conditions.

Common Conditions Monitored

While less common, elevated or low levels of gamma-glutamyl carboxypeptidase might be associated with liver cirrhosis, certain genetic disorders affecting amino acid metabolism, or rare enzyme deficiencies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Gamma-Glutamyl Carboxypeptidase Level

Frequently asked questions

What causes abnormal gamma-glutamyl carboxypeptidase levels?
Abnormal levels may result from liver disease, genetic enzyme disorders, or conditions affecting amino acid metabolism. Your provider will consider your symptoms, medical history, and other test results to determine the cause.
How often should this test be repeated?
Frequency depends on your clinical situation. Your healthcare provider will decide based on your symptoms, test results, and ongoing medical needs. Follow-up may be scheduled if initial results are outside expected ranges.
Can lifestyle changes affect this test?
While diet and lifestyle factors may influence amino acid metabolism indirectly, they are less likely to directly impact gamma-glutamyl carboxypeptidase levels. Always discuss lifestyle adjustments with your provider before making changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy