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Serum/plasma concentration of prostatic acid phosphatase (PAP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of prostatic acid phosphatase, an enzyme produced by prostate tissue, which can help assess prostate health or detect prostate-related conditions.

Quick summary

["A PAP test may be used to monitor prostate cancer or rule out prostate issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2785-4
Short code
PG Amn Ql
Synonyms
PG Amn Ql
Category
glucose
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

When Is This Test Done?

Your doctor may order a PAP test if you have symptoms like urinary changes, pain in the pelvic area, or if you’re at higher risk for prostate problems. It may also be used as part of routine screening for men over a certain age or with a family history of prostate cancer.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast before the test, but this is less common for PAP. Your blood will be drawn from a vein, typically in your arm, and you’ll feel a brief pinch. The process takes about 5 minutes.

What the Results Mean

Higher-than-normal levels of PAP can suggest prostate issues, including prostate cancer, inflammation, or infection. However, other conditions (like benign prostatic hyperplasia) can also affect PAP levels. Your doctor will interpret the results in the context of your symptoms and medical history.

Possible Causes of Abnormal Results

Elevated PAP levels may be linked to prostate cancer, prostate infections, or benign prostate growth. Lower-than-normal levels are less common but could indicate certain medications or rare conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

PAP (Serum/Plasma)

Frequently asked questions

Why might my doctor want to check this test?
Your doctor may recommend a PAP test to evaluate symptoms of prostate problems, monitor prostate cancer treatment, or assess risk factors for prostate disease. It’s important to discuss your symptoms and medical history with your healthcare provider before the test.
What does a high PAP level usually indicate?
A high PAP level can signal potential prostate issues, but it doesn’t always mean cancer. Other conditions, like infections or benign growths, can also raise PAP levels. Your doctor will guide you on next steps based on your results and symptoms.
Can diet or medications affect PAP test results?
Some medications, such as certain prostate medications or supplements, may influence PAP levels. Avoiding certain foods or supplements for a short time before testing may help ensure accurate results, but always follow your doctor’s advice.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy