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Phentermine/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine toxicology test that checks for phentermine, an appetite-suppressant medicine, and compares its amount with urine creatinine to account for urine concentration.

Quick summary

["This test can identify recent phentermine exposure, but results should be interpreted with timing, dose, and other clinical factors."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64134-0
Short code
Phentermine/Creat Ur
Synonyms
Phentermine/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This urine test measures phentermine, a prescription appetite-suppressant used for weight management. It also measures creatinine, a waste product used as a reference for urine concentration, so the phentermine result can be interpreted even when the urine is dilute or concentrated.

Why might I need this test?

A clinician or workplace program may order this test to check for recent phentermine use. It may be included when monitoring medication use, investigating drug exposure, or assessing whether a person is taking a weight-loss medicine as prescribed.

How is the test performed?

A urine sample is collected and analyzed in a laboratory. Screening methods may be used first, and any positive finding may be confirmed with a more specific laboratory method.

How do I prepare for the test?

Follow the collection instructions provided by the clinic or testing site and provide the urine sample in the specified container. Do not stop prescribed medication or deliberately change your fluid intake unless your healthcare professional instructs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable phentermine result generally indicates recent exposure to the medicine, although the exact timing cannot be determined from this test alone. An unexpectedly high result relative to urine creatinine may suggest a recent dose, concentrated urine, or medication use that differs from the prescribed plan. A positive result does not by itself prove misuse, toxicity, impaired driving, or another medical condition.

Short name

Urine phentermine test

Frequently asked questions

Does this test measure kidney function?
No. Creatinine is included mainly to help adjust the urine phentermine result for how concentrated or dilute the urine is. Kidney function is assessed with other tests, such as serum creatinine and estimated glomerular filtration rate.
Can I use this test to tell exactly when I took phentermine?
No. Urine results reflect exposure over a period of time, but they cannot identify an exact dose or dose time. Sample timing, hydration, metabolism, and individual differences can all affect the result.
What if I take phentermine exactly as prescribed?
The test can still be positive because it detects the medicine in the urine. Tell the ordering clinician or testing organization about any prescribed medications so the result can be interpreted appropriately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy