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Phosphate and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 17, 2026

Measures phosphate and creatinine in urine collected over 24 hours to assess mineral excretion and help evaluate kidney and bone-related conditions.

Quick summary

["This test estimates how much phosphate your body loses in urine and uses the collection period to improve interpretation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
13795-0
Short code
Phosphate/Creat 24h Ur
Synonyms
Phosphate/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
2.5
Ref high
4.5
Critical range
1 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84100
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures phosphate and creatinine in all urine collected for 24 hours. Phosphate is a mineral important for bones, energy metabolism, and cell function, while creatinine is a waste product made by the muscles.

Why might I need this test?

A clinician may order it to investigate unusual phosphate loss, kidney stone risk, bone or calcium disorders, or changes in kidney function. Results may also help monitor certain medicines or conditions that affect phosphate and calcium balance.

How is the test performed?

You collect all urine for a full 24-hour period in a labeled container provided by the laboratory. The laboratory measures the amount of phosphate and creatinine in the collection, and the results may be interpreted together to account for the amount of urine produced.

How do I prepare for the test?

Follow the laboratory's collection instructions exactly, including the start and end times. Continue your usual diet and medicines unless your clinician tells you otherwise, and ask the laboratory how to store the container and what to do if any urine is missed.

Reference range

Adult: 2.5-4.5 mg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High urinary phosphate can occur with kidney dysfunction, high blood phosphate, reduced parathyroid hormone activity, or certain medicines. Low urinary phosphate can occur when blood phosphate is low, parathyroid hormone is elevated, phosphate is being retained by the kidneys, or intake is reduced. Interpretation depends on blood tests, kidney function, diet, medicines, and the completeness of the urine collection.

Short name

24-Hour Urine Phosphate and Creatinine

Frequently asked questions

Why is a 24-hour urine collection used?
It measures total excretion over a complete day, which can be more informative than a single urine sample. The exact start and end times are important for accurate results.
Does this test require fasting?
Fasting is generally not required, but your clinician may give special instructions if the test is being used to assess a specific metabolic or bone condition. Follow the laboratory's directions.
What can affect the results?
Missed urine, collection over more or less than 24 hours, changes in diet, dehydration, kidney function, and certain medicines can affect the results. Tell your clinician about relevant medicines and supplements, including phosphate or calcium products.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy