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Urine Phosphate-to-Creatinine Ratio (Calculated)

Published: August 9, 2026Updated: August 17, 2026

A urine test that compares phosphate with creatinine to help assess phosphate excretion and account for how concentrated or dilute the urine is.

Quick summary

["This ratio helps determine how much phosphate is being lost in the urine relative to creatinine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
56964-0
Short code
Phosphate/Creat Ur-Rto
Synonyms
Phosphate/Creat Ur-Rto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
2.5
Ref high
4.5
Critical range
1 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84100
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

The urine phosphate-to-creatinine ratio is a calculated test that compares the amount of phosphate in a urine sample with the amount of creatinine. Creatinine is used as a reference because it is usually released at a relatively steady rate, helping adjust for differences in urine concentration.

Why might I need this test?

Your clinician may use this test when evaluating high or low blood phosphate, kidney stone risk, or conditions that affect how the kidneys and bones handle phosphate. It can also help identify whether too much phosphate is being lost in the urine.

How is the test performed?

A urine sample is tested to measure phosphate and creatinine, and the laboratory calculates their ratio. The order may specify a single urine sample or a timed collection, so follow the collection instructions provided by your healthcare professional.

How do I prepare for the test?

Fasting is generally not required unless your clinician specifically requests it. Continue your normal diet and medications unless instructed otherwise, and be sure to complete any timed urine collection exactly as directed.

Reference range

Adult: 2.5-4.5 mg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A high ratio may indicate that increased amounts of phosphate are being excreted, which can occur with high dietary intake, medications, or conditions that alter phosphate handling. A low ratio may occur with reduced phosphate intake, increased kidney reabsorption, or very dilute urine. Age, kidney function, diet, and the type of urine collection can affect the result, so it should be interpreted alongside your other laboratory tests and medical history.

Short name

Urine phosphate/creatinine ratio

Frequently asked questions

What does the phosphate-to-creatinine ratio measure?
It measures urine phosphate relative to urine creatinine. The ratio helps reduce the effect of variations in how concentrated the urine is.
Why might my phosphate-to-creatinine ratio be abnormal?
Possible factors include diet, medications, kidney function, bone or hormone disorders, and changes in urine concentration. Your clinician will interpret the result in the context of your medical history and other tests.
Do I need to collect all of my urine for 24 hours?
It depends on the laboratory order. Some results use a single urine sample, while others require a timed collection; follow the specific instructions provided with the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy