Skip to content

Platelet Blood Count with Automated Differential Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of platelets in your blood and evaluates the proportions of different white blood cell types (neutrophils, lymphocytes, monocytes, eosinophils, and basophils) using automated technology.

Quick summary

["Helps assess blood health and detect infections, bleeding disorders, or immune system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107193-5
Short code
Platelet # Bld Auto
Synonyms
Platelet # Bld Auto
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
150
Ref high
400
Critical range
50 N/A – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85049
SNOMED
900000000000003003
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order this test to diagnose or monitor conditions like low platelet counts (thrombocytopenia), high platelet counts (thrombocytosis), infections, inflammatory diseases, or blood disorders. It may also be used before surgeries or treatments that affect the immune or blood systems.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally. If you’re on blood-thinning medications, check with your doctor first, as they may need to adjust timing or dosage.

During the Test

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually takes only a few seconds. The blood is then sent to a lab for automated analysis.

What the Results Mean

Results provide two main pieces of information: platelet count and white blood cell differential. Platelet counts below normal may indicate bleeding risks, while elevated counts could signal infections or clotting disorders. Differential counts help identify specific types of white blood cells that may be elevated or low due to illness or immune response.

Reference range

Adult: 150-400 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Platelet & Differential Count

Frequently asked questions

What causes low platelet counts?
Low platelet counts (thrombocytopenia) can result from medications, liver disease, autoimmune disorders, infections, or conditions like leukemia. Symptoms may include easy bruising, prolonged bleeding, or fatigue.
What causes high platelet counts?
High platelet counts (thrombocytosis) may occur due to infections, inflammation, certain cancers, or blood disorders. Symptoms can include fatigue, dizziness, or an increased risk of blood clots.
How often should I get this test?
Frequency depends on your health condition. Doctors may recommend regular monitoring if you have chronic diseases like cancer, kidney disease, or autoimmune disorders. Follow-up tests are often scheduled every few months or as needed for treatment adjustments.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy