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Platelet Aggregation (or Clumping) Assay in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures how platelets in your blood clump together when exposed to certain triggers, helping assess your risk of blood clots or bleeding disorders.

Quick summary

["This test helps evaluate platelet function and potential clotting risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104700-0
Short code
Platelet Clump Bld Ql
Synonyms
Platelet Clump Bld Ql
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
150
Ref high
400
Critical range
50 N/A – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85049
SNOMED
900000000000003003
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Platelets are tiny cells in your blood that help stop bleeding by clumping together to form clots. This test checks how well they clump under controlled conditions, often using a substance like adenosine diphosphate (ADP) or collagen to simulate natural triggers.

Why Might You Need This Test?

You may need this test if you have symptoms like unexplained bruising, prolonged bleeding, or a history of clots. Doctors also use it to monitor treatments for conditions like thrombocytopenia (low platelet count) or blood clotting disorders.

Common Uses in Medical Care

This test is commonly used in diagnosing or monitoring bleeding disorders, platelet dysfunction, or evaluating responses to medications that affect platelet activity, such as antiplatelet drugs.

What to Expect Before the Test

No special preparation is usually needed, but your doctor may ask you to stop certain medications (like aspirin) for a few days before testing, as they can affect platelet function.

Reference range

Adult: 150-400 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Platelet clumping is critical for diagnosing conditions like von Willebrand disease, Bernard-Soulier syndrome, or Glanzmann’s thrombasthenia, where platelets don’t clump properly. It also helps assess bleeding risks in patients on anticoagulants or antiplatelet therapies.

Short name

Platelet Clumping Test (bld)

Frequently asked questions

How is the test performed?
A small sample of your blood is drawn and placed in a machine that measures how quickly and strongly platelets clump together when exposed to specific triggers. The results help determine if your platelets function normally or if there’s an issue with clotting.
What do the results mean?
Results may show normal platelet clumping, reduced clumping (indicating potential bleeding disorder), or excessive clumping (which could suggest a clotting risk). Your doctor will interpret the results in the context of your symptoms and medical history.
Can I eat or drink before the test?
You can typically eat and drink normally before this test, but always follow your doctor’s specific instructions, especially if they mention avoiding certain medications or foods that might affect blood clotting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy