Cerebrospinal Fluid (CSF) Vitamin B6 (Pyridoxine) Pattern Analysis
This test measures the levels and patterns of vitamin B6 (pyridoxine) in your cerebrospinal fluid (CSF), which is the fluid surrounding your brain and spinal cord. It helps assess how well your body is processing this essential nutrient in the central nervous system.
["Vitamin B6 in CSF may be checked if you have neurological symptoms or suspected metabolic issues."]
Key facts at a glance
- LOINC
- 79345-5
- Short code
- PLP + PL + Vit B6 pattern CSF-Imp
- Synonyms
- PLP + PL + Vit B6 pattern CSF-Imp
- Category
- electrolyte
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like nerve pain, seizures, or developmental delays in children. It could also be used to evaluate conditions affecting vitamin B6 metabolism, such as certain genetic disorders or malabsorption issues. Rarely, it may be part of broader investigations for neurological diseases like multiple sclerosis or encephalitis.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your back to collect a small amount of CSF. This is typically done in a hospital or clinic setting and may cause mild discomfort. You’ll lie still for a few minutes afterward to prevent bleeding.
What the Test Results Mean
The test analyzes the concentration and potential patterns of vitamin B6 in your CSF. While specific reference ranges aren’t provided here, abnormal levels may indicate vitamin B6 deficiency or dysfunction in how your body uses it in the brain. Your provider will interpret results in the context of your symptoms and medical history.
Common Conditions Monitored
This test is not a routine screening but may be part of investigations for conditions like pyridoxine-responsive epilepsy, hereditary vitamin B6 deficiency, or metabolic disorders affecting the nervous system. It’s also sometimes used in research or specialized care for rare genetic disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Vitamin B6 Profile
Frequently asked questions
What does it mean if my vitamin B6 levels are low in CSF?
Could this test help diagnose a neurological disorder?
Why would a doctor order this test if vitamin B6 is usually measured in blood?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy