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Prostate-Specific Antigen (PSA)/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures urine PSA relative to urine creatinine, which helps account for differences in urine concentration when monitoring prostate health.

Quick summary

["This urine test tracks PSA over time while adjusting for how concentrated the urine is."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72791-7
Short code
PPAA/Creat Ur
Synonyms
PPAA/Creat Ur
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures prostate-specific antigen (PSA) in urine and compares it with the amount of creatinine in the same sample. Creatinine is used to help account for variations in urine concentration.

Why might I need this test?

A urine PSA-to-creatinine ratio may be used to evaluate the prostate and monitor for changes over time. It may be especially useful when blood PSA results need to be interpreted alongside another measure or when following prostate cancer.

How is the test performed?

You provide a urine sample, which the laboratory analyzes for PSA and creatinine. The laboratory then calculates the PSA-to-creatinine ratio.

How do I prepare for the test?

Fasting is generally not required. Follow your clinician's instructions about collection timing and amount, and tell the laboratory if you recently had prostate testing, surgery, or other procedures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine PSA/Creatinine Ratio

Frequently asked questions

Does this test replace the blood PSA test?
No. It provides information about urine PSA while adjusting for urine concentration and may complement, rather than replace, blood testing.
Is fasting required for a urine PSA-to-creatinine ratio?
Fasting is usually not necessary, but your clinician may provide specific collection instructions.
Does an abnormal result mean I have prostate cancer?
No. An abnormal result can have several causes, including benign prostate conditions, and additional testing may be needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy